Zeno Pathology

Reimagine Cancer Diagnosis With AI

What is Zeno Pathology?

Zeno Pathology provides users with a fully automated AI analysis pipeline that performs whole slide image analysis as a background task. It can be integrated into your existing digital workflow to achieve seamless integration to all relevant clinical / administration systems, therefore enhancing your overall workflow for H&E and IHC whole slide image analysis. Zeno Pathology is able to automatically read any digital slide scanner proprietary image format.

Our modules

Automated Ki-67 Proliferation Index (IHC) - Breast Cancer

Automated tumour cell detection with Ki-67 status classification

One click hot-spot detection based on clinical constraints (number of cells/region area)

Automated selection of any region size (limitless cell count)

Pearson correlation score of true Proliferation Index Score of 0.933 (p < 1e-4) for the validation set 1 and 0.843 (p < 1e-4) for validation set 2

Automated Her2 Score from H&E - Breast Cancer

Automatic Her2 score on H&E stained whole slide images

Providing three scores on the whole slide:

Negative – 0+ & 1+
Equivocal – 2+
Positive – 3+

Automated Ki-67 Proliferation Index (IHC) - Various Cancer Types

Automated tumour cell detection with Ki-67 status classification

Automated multiple hot-spot detection based on clinical constraints (number of cells/region area)

Automated selection of any region size (limitless cell count)

All the modules from Zeno Pathology are available in the EU as a CE-IVD marked medical device. Outside the EU, all modules are Research Use Only and therefore not for use in diagnostic procedures.

The added value of Zeno Pathology

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Seamless integration

Zeno Pathology is developed as a flexible solution, therefore we adjust to what you need. We can integrate Zeno Pathology fully or partially based on your requirements, therefore enhancing your digital workflow instantly.

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The power of deep learning

Zeno Pathology will increase the speed, accuracy and consistency of whole slide image analysis with the power of deep learning algorithms. For the analysis of our modules, we follow the expert guidelines in analysing specific biomarkers on breast cancer tissue.

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Image format

Zeno Pathology is able to automatically read any vendor specific proprietary image formats. With this functionality you can use Zeno Pathology in combination with the most common whole slide image formats.

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Modular approach

Zeno Pathology provides a modular setup, therefore making it possible for you to use whatever is needed. As we are constantly enhancing our range of available modules, you can always add more along the way.

Integration options

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Full workflow intergration

Get the full benefit of Zeno Pathology as an automated AI analysis pipeline to enhance your daily work instantly.

Zeno Pathology can be implemented into your existing digital imaging system, LIS/PIS, communicates with HIS/EMR and provides the enhanced features to deliver seamless reports on top of the results in your slide viewer.

We provide on-premise or cloud installations to adjust to your digital needs.

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Standalone integration

Standalone integration is also possible if a full integration is not feasible. Zeno Pathology is designed as a flexible AI solution to cater to your specific requirements.

Zeno Pathology can be integrated as a standalone AI solution. The image analyses are made via a manual upload of your images into the Zeno Pathology environment.

We provide on-premise or cloud installations to adjust to your digital needs.

Integration partners

How Zeno Pathology works

Using Zeno Pathology will save manual analysis time on whole slide images, as Zeno Pathology is able to automatically analyse H&E and IHC stained whole slide images using state-of-the-art AI algorithms. Zeno Pathology is able to read any image format automatically, which enables you to analyse your H&E and IHC stained whole slide images faster without manual conversion. The flexibility of Zeno Pathology also enables a full or partial integration into your existing clinical workflow which instantly will enhance your daily work.

By using Zeno Pathology, you reduce the observer variability (inter and intra) when analyzing whole slide images. You are able to objectively obtain results that can be used for clinical or research purposes. It will increase the speed, quality and consistency of obtaining your results and creates a solution that can be used to standardize your scoring methods.

Easy to use

Watch the video to see how easy it is to use Zeno Pathology.